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Differential regulation of the Rac1 GTPase–activating protein (GAP) BCR during oxygen/glucose deprivation in hippocampal and cortical neurons

Brain ischemia causes oxygen and glucose deprivation (OGD) in neurons, triggering a cascade of events leading to synaptic accumulation of glutamate. Excessive activation of glutamate receptors causes excitotoxicity and delayed cell death in vulnerable neurons. Following global cerebral ischemia, hip...

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Detalles Bibliográficos
Autores principales:	Smith, Katharine R., Rajgor, Dipen, Hanley, Jonathan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724004/ https://www.ncbi.nlm.nih.gov/pubmed/29046349 http://dx.doi.org/10.1074/jbc.M117.796292

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