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KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis

A deeper understanding of the metastatic process is required for the development of new therapies that improve patient survival. Metastatic tumor cell growth and survival in distant organs is facilitated by the formation of a pre-metastatic niche composed of hematopoietic cells, stromal cells, and e...

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Detalles Bibliográficos
Autores principales: Murgai, Meera, Ju, Wei, Eason, Matthew, Kline, Jessica, Beury, Daniel, Kaczanowska, Sabina, Miettinen, Markku M, Kruhlak, Michael, Lei, Haiyan, Shern, Jack F, Cherepanova, Olga A., Owens, Gary K, Kaplan, Rosandra N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724390/
https://www.ncbi.nlm.nih.gov/pubmed/28920957
http://dx.doi.org/10.1038/nm.4400