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G protein‐coupled receptor 37‐like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia

We show that the G protein‐coupled receptor GPR37‐like 1 (GPR37L1) is expressed in most astrocytes and some oligodendrocyte precursors in the mouse central nervous system. This contrasts with GPR37, which is mainly in mature oligodendrocytes. Comparison of wild type and Gpr37l1(–/–) mice showed that...

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Detalles Bibliográficos
Autores principales: Jolly, Sarah, Bazargani, Narges, Quiroga, Alejandra C., Pringle, Nigel P., Attwell, David, Richardson, William D., Li, Huiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724489/
https://www.ncbi.nlm.nih.gov/pubmed/28795439
http://dx.doi.org/10.1002/glia.23198