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Probing Human Telomeric DNA and RNA Topology and Ligand Binding in a Cellular Model by Using Responsive Fluorescent Nucleoside Probes

The development of biophysical systems that enable an understanding of the structure and ligand‐binding properties of G‐quadruplex (GQ)‐forming nucleic acid sequences in cells or models that mimic the cellular environment would be highly beneficial in advancing GQ‐directed therapeutic strategies. He...

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Detalles Bibliográficos
Autores principales: Manna, Sudeshna, Panse, Cornelia H., Sontakke, Vyankat A., Sangamesh, Sarangamath, Srivatsan, Seergazhi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724660/
https://www.ncbi.nlm.nih.gov/pubmed/28569423
http://dx.doi.org/10.1002/cbic.201700283