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Generation and phenotypic characterisation of a cytochrome P450 4x1 knockout mouse

Cytochrome P450 4x1 (Cyp4x1) is expressed at very high levels in the brain but the function of this protein is unknown. It has been hypothesised to regulate metabolism of fatty acids and to affect the activity of endocannabinoid signalling systems, which are known to influence appetite and energy me...

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Detalles Bibliográficos
Autores principales: Kharkwal, Himanshu, Batool, Farhat, Koentgen, Frank, Bell, David R., Kendall, David A., Ebling, Francis J. P., Duce, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724839/
https://www.ncbi.nlm.nih.gov/pubmed/29227996
http://dx.doi.org/10.1371/journal.pone.0187959