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Dynamical compensation and structural identifiability of biological models: Analysis, implications, and reconciliation

The concept of dynamical compensation has been recently introduced to describe the ability of a biological system to keep its output dynamics unchanged in the face of varying parameters. However, the original definition of dynamical compensation amounts to lack of structural identifiability. This is...

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Detalles Bibliográficos
Autores principales: Villaverde, Alejandro F., Banga, Julio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724898/
https://www.ncbi.nlm.nih.gov/pubmed/29186132
http://dx.doi.org/10.1371/journal.pcbi.1005878