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Low concentration of formononetin promotes proliferation of estrogen receptor-positive cells through an ERα-miR-375-PTEN-ERK1/2-bcl-2 pathway

A low dose of formononetin accelerates the proliferation of nasopharyngeal carcinoma cells in vitro; however, the underlying mechanism remains unknown. Here, we investigated the molecular mechanism of formononetin in CNE2 cell proliferation. CNE2 cells were treated with 0 to 1 μM formononetin. To in...

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Detalles Bibliográficos
Autores principales: Guo, Yan-Hong, Tang, Feng-Yan, Wang, Yong, Huang, Wen-Jun, Tian, Jing, Lu, Hui-Ling, Xin, Min, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725001/
https://www.ncbi.nlm.nih.gov/pubmed/29245959
http://dx.doi.org/10.18632/oncotarget.21923