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Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells

Impaired Wnt signaling pathway plays a crucial role in the development of colorectal cancer through activation of the β-catenin/TCF7L2 complex. Although genes up-regulated by Wnt/β-catenin signaling have been intensively studied, the roles of down-regulated genes are poorly understood. In this study...

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Detalles Bibliográficos
Autores principales: Ohsugi, Tomoyuki, Yamaguchi, Kiyoshi, Zhu, Chi, Ikenoue, Tsuneo, Furukawa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725011/
https://www.ncbi.nlm.nih.gov/pubmed/29245969
http://dx.doi.org/10.18632/oncotarget.22122