Cargando…

Calcitriol induces cell senescence of kidney cancer through JMJD3 mediated histone demethylation

Calcitriol, also known as 1,25-dihydroxyvitamin D3 (1,25(OH)(2)VD(3)), is a biologically active form of vitamin D and has a wide range of anticancer activity against various cancer cell lines. However, the mechanism of calcitriol remains to be further studied. In this study, the biological effect an...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yongqing, Yu, Dan, Qi, Pan, Wang, Xuliang, Guo, Xiaoqiang, Zhang, Aili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725012/
https://www.ncbi.nlm.nih.gov/pubmed/29245970
http://dx.doi.org/10.18632/oncotarget.22124