An anti-CAPN5 intracellular antibody acts as an inhibitor of CAPN5-mediated neuronal degeneration

CAPN5 has been linked to autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV). Activation of CAPN5 may increase proteolysis and degradation of a wide range of substrates to induce degeneration in the retina and the nerve system. Thus, we developed an inhibitory intracellular single...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Zhang, Xiao, Song, Zongming, Gu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725022/
https://www.ncbi.nlm.nih.gov/pubmed/29245980
http://dx.doi.org/10.18632/oncotarget.22221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725022/
https://www.ncbi.nlm.nih.gov/pubmed/29245980
http://dx.doi.org/10.18632/oncotarget.22221

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