Cargando…
An anti-CAPN5 intracellular antibody acts as an inhibitor of CAPN5-mediated neuronal degeneration
CAPN5 has been linked to autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV). Activation of CAPN5 may increase proteolysis and degradation of a wide range of substrates to induce degeneration in the retina and the nerve system. Thus, we developed an inhibitory intracellular single...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725022/ https://www.ncbi.nlm.nih.gov/pubmed/29245980 http://dx.doi.org/10.18632/oncotarget.22221 |