Endothelial-derived interleukin-6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

Recent evidence suggests that the metastatic spread of head and neck squamous cell carcinomas (HNSCC) requires the function of cancer stem cells endowed with multipotency, self-renewal, and high tumorigenic potential. We demonstrated that cancer stem cells reside in perivascular niches and are chara...

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Detalles Bibliográficos
Autores principales: Kim, Hong Sun, Chen, Yu-Chih, Nör, Felipe, Warner, Kristy A., Andrews, April, Wagner, Vivian P., Zhang, Zhaocheng, Zhang, Zhixiong, Martins, Manoela D., Pearson, Alexander T., Yoon, Euisik, Nör, Jacques E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725024/
https://www.ncbi.nlm.nih.gov/pubmed/29245982
http://dx.doi.org/10.18632/oncotarget.22225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725024/
https://www.ncbi.nlm.nih.gov/pubmed/29245982
http://dx.doi.org/10.18632/oncotarget.22225

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