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Endothelial-derived interleukin-6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels
Recent evidence suggests that the metastatic spread of head and neck squamous cell carcinomas (HNSCC) requires the function of cancer stem cells endowed with multipotency, self-renewal, and high tumorigenic potential. We demonstrated that cancer stem cells reside in perivascular niches and are chara...
Autores principales: | Kim, Hong Sun, Chen, Yu-Chih, Nör, Felipe, Warner, Kristy A., Andrews, April, Wagner, Vivian P., Zhang, Zhaocheng, Zhang, Zhixiong, Martins, Manoela D., Pearson, Alexander T., Yoon, Euisik, Nör, Jacques E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725024/ https://www.ncbi.nlm.nih.gov/pubmed/29245982 http://dx.doi.org/10.18632/oncotarget.22225 |
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