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Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity

Personalized cancer medicine based on the analysis of tumors en masse is limited by tumor heterogeneity, which has become a major obstacle to effective cancer treatment. Cancer stem cells (CSC) are emerging as key drivers of inter- and intratumoral heterogeneity. CSC have unique metabolic dependenci...

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Detalles Bibliográficos
Autores principales: Cuyàs, Elisabet, Verdura, Sara, Fernández-Arroyo, Salvador, Bosch-Barrera, Joaquim, Martin-Castillo, Begoña, Joven, Jorge, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725087/
https://www.ncbi.nlm.nih.gov/pubmed/29245896
http://dx.doi.org/10.18632/oncotarget.21834