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Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity
Personalized cancer medicine based on the analysis of tumors en masse is limited by tumor heterogeneity, which has become a major obstacle to effective cancer treatment. Cancer stem cells (CSC) are emerging as key drivers of inter- and intratumoral heterogeneity. CSC have unique metabolic dependenci...
Autores principales: | Cuyàs, Elisabet, Verdura, Sara, Fernández-Arroyo, Salvador, Bosch-Barrera, Joaquim, Martin-Castillo, Begoña, Joven, Jorge, Menendez, Javier A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725087/ https://www.ncbi.nlm.nih.gov/pubmed/29245896 http://dx.doi.org/10.18632/oncotarget.21834 |
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