COX-2 metabolic products, the prostaglandin I(2) and F(2α), mediate the effects of TNF-α and Zn(2+) in stimulating the phosphorylation of Tau

Although the roles of cyclooxygenase-2 (COX-2) and prostaglandins (PGs) in regulating amyloid precursor protein (APP) cleavage and β-amyloid protein (Aβ) production have been the subjects of numerous investigations, their effects on tau phosphorylation have been largely overlooked. Using human Tau(P...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Guan, Pei-Pei, Yu, Xin, Guo, Yan-Su, Zhang, Ying-Jie, Wang, Zhan-You, Wang, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Gerotarget(Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725093/
https://www.ncbi.nlm.nih.gov/pubmed/29245902
http://dx.doi.org/10.18632/oncotarget.21853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725093/
https://www.ncbi.nlm.nih.gov/pubmed/29245902
http://dx.doi.org/10.18632/oncotarget.21853

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