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Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACE-induced hypoxia: A biopsy and resection matched study

BACKGROUND: Hepatocellular carcinomas (HCCs) expressing stemness markers are characterized by an aggressive behavior, which might be promoted by an altered tumor stroma. Transarterial chemoembolization (TACE) induces severe hypoxia, and its effect on stemness and tumor stroma of HCCs remains unclear...

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Detalles Bibliográficos
Autores principales: Nahm, Ji Hae, Rhee, Hyungjin, Kim, Haeryoung, Yoo, Jeong Eun, San Lee, Jee, Jeon, Youngsic, Choi, Gi Hong, Park, Young Nyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725098/
https://www.ncbi.nlm.nih.gov/pubmed/29245907
http://dx.doi.org/10.18632/oncotarget.22078