Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species

The present studies focused on the ability of the phosphodiesterase 5 (PDE5) inhibitor sildenafil to enhance the anti-cancer properties of clinically relevant concentrations of the dietary diarylheptanoid curcumin. In gastrointestinal tumor cells, sildenafil and curcumin interacted in a greater than...

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Detalles Bibliográficos
Autores principales: Roberts, Jane L., Poklepovic, Andrew, Booth, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725106/
https://www.ncbi.nlm.nih.gov/pubmed/29245915
http://dx.doi.org/10.18632/oncotarget.19807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725106/
https://www.ncbi.nlm.nih.gov/pubmed/29245915
http://dx.doi.org/10.18632/oncotarget.19807

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