Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells

ZEB1, a member of the zinc-finger E-box binding homeobox family, is considered to play a crucial role in cancer progression and metastasis. In the current study, we investigated the role of ZEB1 in metastasis and chronic chemoresistance of epithelial ovarian carcinoma (EOC) cells. Using several EOC...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakata, Jun, Utsumi, Fumi, Suzuki, Shiro, Niimi, Kaoru, Yamamoto, Eiko, Shibata, Kiyosumi, Senga, Takeshi, Kikkawa, Fumitaka, Kajiyama, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725108/
https://www.ncbi.nlm.nih.gov/pubmed/29245917
http://dx.doi.org/10.18632/oncotarget.20107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725108/
https://www.ncbi.nlm.nih.gov/pubmed/29245917
http://dx.doi.org/10.18632/oncotarget.20107

Ejemplares similares