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Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway

Icariin (ICA) is a major component isolated from Epimedium brevicornum. Emerging evidence shows that ICA can inhibit tumor cell proliferation, invasion and migration. However, the anti-cancer effect of ICA on B16 cells has not been fully investigated. Here we found that the proliferation of B16 cell...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Xu, Wenjuan, Chen, Xiaoyu, Han, Jichun, Yu, Lina, Gao, Caixia, Hao, Wenjin, Liu, Xiaona, Zheng, Qiusheng, Li, Defang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725110/
https://www.ncbi.nlm.nih.gov/pubmed/29245919
http://dx.doi.org/10.18632/oncotarget.20118