The quinone-based derivative, HMNQ induces apoptotic and autophagic cell death by modulating reactive oxygen species in cancer cells

8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ), a natural compound isolated from the bark of Juglans sinensis Dode, displays cytotoxic activity against various human cancer cells. However, the molecular mechanism of the anticancer effect is unclear. In this study, we examined the cytotoxic mechanism...

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Detalles Bibliográficos
Autores principales: Lee, Eun Byul, Cheon, Min Gyeong, Cui, Jun, Lee, Yoo Jin, Seo, Eun Kyoung, Jang, Ho Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725121/
https://www.ncbi.nlm.nih.gov/pubmed/29245930
http://dx.doi.org/10.18632/oncotarget.21005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725121/
https://www.ncbi.nlm.nih.gov/pubmed/29245930
http://dx.doi.org/10.18632/oncotarget.21005

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