mir-193 targets ALDH2 and contributes to toxic aldehyde accumulation and tyrosine hydroxylase dysfunction in cerebral ischemia/reperfusion injury

MicroRNAs (miRNAs, miR) play a fundamental role in cerebral ischemia/reperfusion (I/R) injury. However, the role of miRNAs in toxic aldehyde and tyrosine accumulation is not fully elucidated. We constructed a cerebral I/R rat model and found that overexpression of miR-193 was associated with the acc...

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Detalles Bibliográficos
Autores principales: Mao, Li, Zuo, Mei-Ling, Hu, Guo-Huang, Duan, Xiao-Ming, Yang, Zhong-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725124/
https://www.ncbi.nlm.nih.gov/pubmed/29245933
http://dx.doi.org/10.18632/oncotarget.21129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725124/
https://www.ncbi.nlm.nih.gov/pubmed/29245933
http://dx.doi.org/10.18632/oncotarget.21129

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