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mir-193 targets ALDH2 and contributes to toxic aldehyde accumulation and tyrosine hydroxylase dysfunction in cerebral ischemia/reperfusion injury

MicroRNAs (miRNAs, miR) play a fundamental role in cerebral ischemia/reperfusion (I/R) injury. However, the role of miRNAs in toxic aldehyde and tyrosine accumulation is not fully elucidated. We constructed a cerebral I/R rat model and found that overexpression of miR-193 was associated with the acc...

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Detalles Bibliográficos
Autores principales:	Mao, Li, Zuo, Mei-Ling, Hu, Guo-Huang, Duan, Xiao-Ming, Yang, Zhong-Bao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725124/ https://www.ncbi.nlm.nih.gov/pubmed/29245933 http://dx.doi.org/10.18632/oncotarget.21129

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