PD-1/PD-L1 interaction up-regulates MDR1/P-gp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways

Programmed cell death ligand 1 (PD-L1) is an immunosuppressive molecule expressed on tumor cells. By interacting with programmed cell death-1 (PD-1) on T cells, it inhibits immune responses. Because PD-L1 expression on cancer cells increases their chemoresistance, we investigated the correlation bet...

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Detalles Bibliográficos
Autores principales: Liu, Shengwei, Chen, Shuang, Yuan, Weiguang, Wang, Hongyan, Chen, Kewang, Li, Dianjun, Li, Dalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725139/
https://www.ncbi.nlm.nih.gov/pubmed/29245948
http://dx.doi.org/10.18632/oncotarget.21914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725139/
https://www.ncbi.nlm.nih.gov/pubmed/29245948
http://dx.doi.org/10.18632/oncotarget.21914

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