The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages

Müllerian inhibiting substance, also called anti-Müllerian hormone (AMH), inhibits proliferation and induces apoptosis of AMH type II receptor-positive tumor cells, such as human ovarian cancers (OCs). On this basis, a humanized glyco-engineered monoclonal antibody (3C23K) has been developed. The ai...

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Detalles Bibliográficos
Autores principales: Bougherara, Houcine, Némati, Fariba, Nicolas, André, Massonnet, Gérald, Pugnière, Martine, Ngô, Charlotte, Le Frère-Belda, Marie-Aude, Leary, Alexandra, Alexandre, Jérôme, Meseure, Didier, Barret, Jean-Marc, Navarro-Teulon, Isabelle, Pèlegrin, André, Roman-Roman, Sergio, Prost, Jean-François, Donnadieu, Emmanuel, Decaudin, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725143/
https://www.ncbi.nlm.nih.gov/pubmed/29245952
http://dx.doi.org/10.18632/oncotarget.21556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725143/
https://www.ncbi.nlm.nih.gov/pubmed/29245952
http://dx.doi.org/10.18632/oncotarget.21556

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