Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

PURPOSE: African Americans have a higher incidence and mortality from colorectal cancer. This disparity might be due, in part, to the type of mutations in driver genes. In this study, we examined alterations specific to APC, MSH3, and MSH6 genes using targeted exome sequencing to determine distincti...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashktorab, Hassan, Azimi, Hamed, Varma, Sudhir, Tavakoli, Payaam, Nickerson, Michael L., Brim, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725144/
https://www.ncbi.nlm.nih.gov/pubmed/29245953
http://dx.doi.org/10.18632/oncotarget.21557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725144/
https://www.ncbi.nlm.nih.gov/pubmed/29245953
http://dx.doi.org/10.18632/oncotarget.21557

Ejemplares similares