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Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia
PURPOSE: African Americans have a higher incidence and mortality from colorectal cancer. This disparity might be due, in part, to the type of mutations in driver genes. In this study, we examined alterations specific to APC, MSH3, and MSH6 genes using targeted exome sequencing to determine distincti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725144/ https://www.ncbi.nlm.nih.gov/pubmed/29245953 http://dx.doi.org/10.18632/oncotarget.21557 |