Role of Dopamine Receptors in the Anticancer Activity of ONC201()()

ONC201/TIC10 is a first-in-class small molecule inducer of TRAIL that causes early activation of the integrated stress response. Its promising safety profile and broad-spectrum efficacy in vitro have been confirmed in Phase I/II trials in several advanced malignancies. Binding and reporter assays ha...

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Detalles Bibliográficos
Autores principales: Kline, Christina Leah B., Ralff, Marie D., Lulla, Amriti R., Wagner, Jessica M., Abbosh, Phillip H., Dicker, David T., Allen, Joshua E., El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725157/
https://www.ncbi.nlm.nih.gov/pubmed/29216597
http://dx.doi.org/10.1016/j.neo.2017.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725157/
https://www.ncbi.nlm.nih.gov/pubmed/29216597
http://dx.doi.org/10.1016/j.neo.2017.10.002

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