Metabolic re-patterning in COPD airway smooth muscle cells

Chronic obstructive pulmonary disease (COPD) airways are characterised by thickening of airway smooth muscle, partly due to airway smooth muscle cell (ASMC) hyperplasia. Metabolic reprogramming involving increased glycolysis and glutamine catabolism supports the biosynthetic and redox balance requir...

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Detalles Bibliográficos
Autores principales: Michaeloudes, Charalambos, Kuo, Chih-Hsi, Haji, Gulam, Finch, Donna K., Halayko, Andrew J., Kirkham, Paul, Chung, Kian Fan, Adcock, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725208/
https://www.ncbi.nlm.nih.gov/pubmed/29191950
http://dx.doi.org/10.1183/13993003.00202-2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725208/
https://www.ncbi.nlm.nih.gov/pubmed/29191950
http://dx.doi.org/10.1183/13993003.00202-2017

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