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Metabolic re-patterning in COPD airway smooth muscle cells
Chronic obstructive pulmonary disease (COPD) airways are characterised by thickening of airway smooth muscle, partly due to airway smooth muscle cell (ASMC) hyperplasia. Metabolic reprogramming involving increased glycolysis and glutamine catabolism supports the biosynthetic and redox balance requir...
Autores principales: | Michaeloudes, Charalambos, Kuo, Chih-Hsi, Haji, Gulam, Finch, Donna K., Halayko, Andrew J., Kirkham, Paul, Chung, Kian Fan, Adcock, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725208/ https://www.ncbi.nlm.nih.gov/pubmed/29191950 http://dx.doi.org/10.1183/13993003.00202-2017 |
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