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TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling

PURPOSE: Tripartite-motif-containing protein 56 (TRIM56) has been found to exhibit a broad antiviral activity, depending upon E3 ligase activity. Here, we attempted to evaluate the function of TRIM56 in multiple myeloma (MM) and its underlying molecular basis. MATERIALS AND METHODS: TRIM56 expressio...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Zhao, Jing, Li, Dengzhe, Hao, Jinxia, He, Pengcheng, Wang, Huaiyu, Zhang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725363/
https://www.ncbi.nlm.nih.gov/pubmed/29214775
http://dx.doi.org/10.3349/ymj.2018.59.1.43