Cargando…

TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling

PURPOSE: Tripartite-motif-containing protein 56 (TRIM56) has been found to exhibit a broad antiviral activity, depending upon E3 ligase activity. Here, we attempted to evaluate the function of TRIM56 in multiple myeloma (MM) and its underlying molecular basis. MATERIALS AND METHODS: TRIM56 expressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ying, Zhao, Jing, Li, Dengzhe, Hao, Jinxia, He, Pengcheng, Wang, Huaiyu, Zhang, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725363/ https://www.ncbi.nlm.nih.gov/pubmed/29214775 http://dx.doi.org/10.3349/ymj.2018.59.1.43

Ejemplares similares

TRIM38 Negatively Regulates TLR3-Mediated IFN-β Signaling by Targeting TRIF for Degradation
por: Xue, Qinghua, et al.
Publicado: (2012)

ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3
por: Zang, Ru, et al.
Publicado: (2020)

Role of Extracellular RNA and TLR3‐Trif Signaling in Myocardial Ischemia–Reperfusion Injury
por: Chen, Chan, et al.
Publicado: (2014)

Autocrine-Paracrine Prostaglandin E(2) Signaling Restricts TLR4 internalization and TRIF Signaling
por: Perkins, Darren J., et al.
Publicado: (2018)

Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages
por: Oldenburg, Reid, et al.
Publicado: (2018)

Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages
por: Palmer, Charys, et al.
Publicado: (2021)

The Ubiquitin-Like Protein PLIC-1 or Ubiquilin 1 Inhibits TLR3-Trif Signaling
por: Biswas, Nabanita, et al.
Publicado: (2011)

SLAMF1 is required for TLR4-mediated TRAM-TRIF–dependent signaling in human macrophages
por: Yurchenko, Maria, et al.
Publicado: (2018)

The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
por: Pereira, Milton, et al.
Publicado: (2022)

Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling
por: Cagliero, Julie, et al.
Publicado: (2022)

To be or not to be: the role of CD56 in multiple myeloma
por: Cottini, Francesca, et al.
Publicado: (2023)

TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses
por: Yang, Qing, et al.
Publicado: (2017)

Macrophage deletion of Noc4l triggers endosomal TLR4/TRIF signal and leads to insulin resistance
por: Qin, Yongli, et al.
Publicado: (2021)

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways
por: Pang, Zheng, et al.
Publicado: (2018)

TRIF Is Required for TLR4 Mediated Adjuvant Effects on T Cell Clonal Expansion
por: Gandhapudi, Siva K., et al.
Publicado: (2013)

RP105 alleviates myocardial ischemia reperfusion injury via inhibiting TLR4/TRIF signaling pathways
por: Yang, Jun, et al.
Publicado: (2018)

Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease
por: Abston, Eric D., et al.
Publicado: (2012)

Both TLR2 and TRIF Contribute to Interferon-β Production during Listeria Infection
por: Aubry, Camille, et al.
Publicado: (2012)

Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis
por: Bierwagen, Jeff, et al.
Publicado: (2023)

Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56
por: Xue, Min, et al.
Publicado: (2019)

TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein
por: Yang, Xu, et al.
Publicado: (2022)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine
por: Ruiz, Jose, et al.
Publicado: (2016)

The Functions of TRIM56 in Antiviral Innate Immunity and Tumorigenesis
por: Fu, Lin, et al.
Publicado: (2023)

TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4
por: Wei, Chuan-Yuan, et al.
Publicado: (2019)

TRIF Is a Critical Negative Regulator of TLR Agonist Mediated Activation of Dendritic Cells In Vivo
por: Seregin, Sergey S., et al.
Publicado: (2011)

ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF
por: Muendlein, Hayley I., et al.
Publicado: (2022)

Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD
por: Qu, Lin, et al.
Publicado: (2011)

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage
por: Lin, Sen, et al.
Publicado: (2012)

Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway
por: Liang, Yisha, et al.
Publicado: (2018)

The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia
por: Lai, Mengyu, et al.
Publicado: (2018)

Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages
por: Owen, Katherine A., et al.
Publicado: (2016)

Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma
por: Lu, Kun, et al.
Publicado: (2021)

Correction: Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway
por: Liang, Yisha, et al.
Publicado: (2018)

Polyguanine alleviated autoimmune hepatitis through regulation of macrophage receptor with collagenous structure and TLR4‐TRIF‐NF‐κB signalling
por: Cai, Tingchen, et al.
Publicado: (2022)

TRIM16 suppresses the progression of prostate tumors by inhibiting the Snail signaling pathway
por: Qi, Li, et al.
Publicado: (2016)

TRIM16 suppresses the progression of prostate tumors by inhibiting the Snail signaling pathway
por: Qi, Li, et al.
Publicado: (2023)

Glaucocalyxin A suppresses multiple myeloma progression in vitro and in vivo through inhibiting the activation of STAT3 signaling pathway
por: Li, Mei, et al.
Publicado: (2021)

The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice
por: Tsutsui, Hiroko, et al.
Publicado: (2010)

Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways
por: Rao, Xiaoquan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8h4705cch62iflotjc6g68lf0g