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Find_tfSBP: find thermodynamics-feasible and smallest balanced pathways with high yield from large-scale metabolic networks

Biologically meaningful metabolic pathways are important references in the design of industrial bacterium. At present, constraint-based method is the only way to model and simulate a genome-scale metabolic network under steady-state criteria. Due to the inadequate assumption of the relationship in g...

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Detalles Bibliográficos
Autores principales: Xu, Zixiang, Sun, Jibin, Wu, Qiaqing, Zhu, Dunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725421/
https://www.ncbi.nlm.nih.gov/pubmed/29229946
http://dx.doi.org/10.1038/s41598-017-17552-2