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Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D(pol)

Most single stranded plus RNA viruses hijack phosphatidylinositol 4-kinases (PI4Ks) to generate membranes highly enriched in phosphatidylinositol 4-phosphate (PI4P). These membranous compartments known as webs, replication factories or replication organelles are essential for viral replication becau...

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Detalles Bibliográficos
Autores principales: Dubankova, Anna, Humpolickova, Jana, Klima, Martin, Boura, Evzen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725453/
https://www.ncbi.nlm.nih.gov/pubmed/29230036
http://dx.doi.org/10.1038/s41598-017-17621-6