Cargando…

High-fat diet-induced obesity impairs insulin signaling in lungs of allergen-challenged mice: Improvement by resveratrol

Insulin resistance plays an important role in obesity-associated asthma exacerbations. Using a murine model of allergic airway inflammation, we evaluated the insulin signaling transmission in lungs of obese compared with lean mice. We further evaluated the effects of the polyphenol resveratrol in th...

Descripción completa

Detalles Bibliográficos
Autores principales: André, Diana M., Calixto, Marina C., Sollon, Carolina, Alexandre, Eduardo C., Tavares, Edith B. G., Naime, Ana C. A., Anhê, Gabriel F., Antunes, Edson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725490/
https://www.ncbi.nlm.nih.gov/pubmed/29229986
http://dx.doi.org/10.1038/s41598-017-17558-w