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High-fat diet-induced obesity impairs insulin signaling in lungs of allergen-challenged mice: Improvement by resveratrol
Insulin resistance plays an important role in obesity-associated asthma exacerbations. Using a murine model of allergic airway inflammation, we evaluated the insulin signaling transmission in lungs of obese compared with lean mice. We further evaluated the effects of the polyphenol resveratrol in th...
Autores principales: | André, Diana M., Calixto, Marina C., Sollon, Carolina, Alexandre, Eduardo C., Tavares, Edith B. G., Naime, Ana C. A., Anhê, Gabriel F., Antunes, Edson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725490/ https://www.ncbi.nlm.nih.gov/pubmed/29229986 http://dx.doi.org/10.1038/s41598-017-17558-w |
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