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Exploring the relationship between polio type 2 serum neutralizing antibodies and intestinal immunity using data from two randomized controlled trials of new bOPV-IPV immunization schedules

BACKGROUND: Inactivated polio vaccine (IPV) is now the only source of routine type 2 protection. The relationship, if any, between vaccine-induced type 2 humoral and intestinal immunity is poorly understood. METHODS: Two clinical trials in five Latin American countries of mixed or sequential bOPV-IP...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Ananda S., Asturias, Edwin J., O'Ryan, Miguel, Oberste, M. Steven, Weldon, William, Clemens, Ralf, Rüttimann, Ricardo, Modlin, John F., Gast, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725506/
https://www.ncbi.nlm.nih.gov/pubmed/29150209
http://dx.doi.org/10.1016/j.vaccine.2017.11.006