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Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer’s disease

INTRODUCTION: There is still a clear need for a widely available, inexpensive and reliable method to diagnose Alzheimer’s disease (AD) and monitor disease progression. Liquid chromatography–mass spectrometry (LC-MS) is a powerful analytic technique with a very high sensitivity and specificity. OBJEC...

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Detalles Bibliográficos
Autores principales: Marksteiner, Josef, Blasko, Imrich, Kemmler, Georg, Koal, Therese, Humpel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725507/
https://www.ncbi.nlm.nih.gov/pubmed/29249916
http://dx.doi.org/10.1007/s11306-017-1297-5