Post-transcriptional 3´-UTR cleavage of mRNA transcripts generates thousands of stable uncapped autonomous RNA fragments

The majority of mammalian genes contain one or more alternative polyadenylation sites. Choice of polyadenylation sites was suggested as one of the underlying mechanisms for generating longer/shorter transcript isoforms. Here, we demonstrate that mature mRNA transcripts can undergo additional cleavag...

Descripción completa

Detalles Bibliográficos
Autores principales: Malka, Yuval, Steiman-Shimony, Avital, Rosenthal, Eran, Argaman, Liron, Cohen-Daniel, Leonor, Arbib, Eliran, Margalit, Hanah, Kaplan, Tommy, Berger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725528/
https://www.ncbi.nlm.nih.gov/pubmed/29229900
http://dx.doi.org/10.1038/s41467-017-02099-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725528/
https://www.ncbi.nlm.nih.gov/pubmed/29229900
http://dx.doi.org/10.1038/s41467-017-02099-7

Ejemplares similares