Common SAR Derived from Linear and Non-linear QSAR Studies on AChE Inhibitors used in the Treatment of Alzheimer’s Disease

BACKGROUND: Deficits in cholinergic neurotransmission due to the degeneration of cholinergic neurons in the brain are believed to be one of the major causes of the memory impairments associated with AD. Targeting acetyl cholinesterase (AChE) surfaced as a potential therapeutic target in the treatmen...

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Detalles Bibliográficos
Autores principales: Pulikkal, Babitha Pallikkara, Marunnan, Sahila Mohammed, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Sureshkumar, Sivanpillai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725541/
https://www.ncbi.nlm.nih.gov/pubmed/27964704
http://dx.doi.org/10.2174/1570159X14666161213142841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725541/
https://www.ncbi.nlm.nih.gov/pubmed/27964704
http://dx.doi.org/10.2174/1570159X14666161213142841

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