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Common SAR Derived from Linear and Non-linear QSAR Studies on AChE Inhibitors used in the Treatment of Alzheimer’s Disease
BACKGROUND: Deficits in cholinergic neurotransmission due to the degeneration of cholinergic neurons in the brain are believed to be one of the major causes of the memory impairments associated with AD. Targeting acetyl cholinesterase (AChE) surfaced as a potential therapeutic target in the treatmen...
Autores principales: | Pulikkal, Babitha Pallikkara, Marunnan, Sahila Mohammed, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Sureshkumar, Sivanpillai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725541/ https://www.ncbi.nlm.nih.gov/pubmed/27964704 http://dx.doi.org/10.2174/1570159X14666161213142841 |
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