Opioids and the Blood-Brain Barrier: A Dynamic Interaction with 
Consequences on Drug Disposition in Brain

BACKGROUND: Opioids are widely used in pain management, acting via opioid receptors and/or Toll-like receptors (TLR) present at the central nervous system (CNS). At the blood-brain barrier (BBB), several influx and efflux transporters, such as the ATP-binding cassette (ABC) P-glycoprotein (P-gp, ABC...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaves, Catarina, Remião, Fernando, Cisternino, Salvatore, Declèves, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725546/
https://www.ncbi.nlm.nih.gov/pubmed/28474563
http://dx.doi.org/10.2174/1570159X15666170504095823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725546/
https://www.ncbi.nlm.nih.gov/pubmed/28474563
http://dx.doi.org/10.2174/1570159X15666170504095823

Ejemplares similares