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Aripiprazole, A Drug that Displays Partial Agonism and Functional Selectivity
BACKGROUND: The treatment of schizophrenia is challenging due to the wide range of symptoms (positive, negative, cognitive) associated with the disease. Typical antipsychotics that antagonize D2 receptors are effective in treating positive symptoms, but extrapyramidal side-effects (EPS) are a common...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725548/ https://www.ncbi.nlm.nih.gov/pubmed/28412910 http://dx.doi.org/10.2174/1570159X15666170413115754 |