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Urinary endotrophin predicts disease progression in patients with chronic kidney disease

Renal fibrosis is the central pathogenic process in progression of chronic kidney disease (CKD). Collagen type VI (COL VI) is upregulated in renal fibrosis. Endotrophin is released from COL VI and promotes pleiotropic pro-fibrotic effects. Kidney disease severity varies considerably and accurate inf...

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Detalles Bibliográficos
Autores principales: Rasmussen, Daniel Guldager Kring, Fenton, Anthony, Jesky, Mark, Ferro, Charles, Boor, Peter, Tepel, Martin, Karsdal, Morten Asser, Genovese, Federica, Cockwell, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725589/
https://www.ncbi.nlm.nih.gov/pubmed/29229941
http://dx.doi.org/10.1038/s41598-017-17470-3