Silica inhalation altered telomere length and gene expression of telomere regulatory proteins in lung tissue of rats

Exposure to silica can cause lung fibrosis and cancer. Identification of molecular targets is important for the intervention and/or prevention of silica-induced lung diseases. Telomeres consist of tandem repeats of DNA sequences at the end of chromosomes, preventing chromosomal fusion and degradatio...

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Detalles Bibliográficos
Autores principales: Shoeb, Mohammad, Joseph, Pius, Kodali, Vamsi, Mustafa, Gul, Farris, Breanne Y., Umbright, Christina, Roberts, Jenny R., Erdely, Aaron, Antonini, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725592/
https://www.ncbi.nlm.nih.gov/pubmed/29230030
http://dx.doi.org/10.1038/s41598-017-17645-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725592/
https://www.ncbi.nlm.nih.gov/pubmed/29230030
http://dx.doi.org/10.1038/s41598-017-17645-y

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