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Gli1 identifies osteogenic progenitors for bone formation and fracture repair

Bone formation in mammals requires continuous production of osteoblasts throughout life. A common molecular marker for all osteogenic mesenchymal progenitors has not been identified. Here, by lineage-tracing experiments in fetal or postnatal mice, we discover that Gli1(+) cells progressively produce...

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Detalles Bibliográficos
Autores principales: Shi, Yu, He, Guangxu, Lee, Wen-Chih, McKenzie, Jennifer A., Silva, Matthew J., Long, Fanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725597/
https://www.ncbi.nlm.nih.gov/pubmed/29230039
http://dx.doi.org/10.1038/s41467-017-02171-2