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BAFF- and APRIL-targeted therapy in systemic autoimmune diseases
B cells play a pivotal role in autoimmunity not only by producing pathogenic autoantibodies but also by modulating immune responses via the production of cytokines and chemokines. The B cell-activating factor/a proliferation-inducing ligand (BAFF/APRIL) system promotes B cell survival and differenti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725651/ https://www.ncbi.nlm.nih.gov/pubmed/29259679 http://dx.doi.org/10.1186/s41232-016-0015-4 |