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Single‐Molecule Monitoring of the Structural Switching Dynamics of Nucleic Acids through Controlling Fluorescence Blinking

Single‐molecule fluorescence resonance energy transfer (smFRET) is a powerful tool to investigate the dynamics of biomolecular events in real time. However, it requires two fluorophores and can be applied only to dynamics that accompany large changes in distance between the molecules. Herein, we int...

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Detalles Bibliográficos
Autores principales: Kawai, Kiyohiko, Miyata, Takafumi, Shimada, Naohiko, Ito, Syoji, Miyasaka, Hiroshi, Maruyama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725658/
https://www.ncbi.nlm.nih.gov/pubmed/28990725
http://dx.doi.org/10.1002/anie.201708705