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Protonation‐Initiated Cyclization by a Class II Terpene Cyclase Assisted by Tunneling
Terpenes represent one of the most diversified classes of natural products with potent biological activities. The key to the myriad of polycyclic terpene skeletons with crucial functions in organisms from all kingdoms of life are terpene cyclase enzymes. These biocatalysts enable stereospecific cycl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725671/ https://www.ncbi.nlm.nih.gov/pubmed/28980755 http://dx.doi.org/10.1002/cbic.201700443 |