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Protonation‐Initiated Cyclization by a Class II Terpene Cyclase Assisted by Tunneling

Terpenes represent one of the most diversified classes of natural products with potent biological activities. The key to the myriad of polycyclic terpene skeletons with crucial functions in organisms from all kingdoms of life are terpene cyclase enzymes. These biocatalysts enable stereospecific cycl...

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Detalles Bibliográficos
Autores principales: Eriksson, Adam, Kürten, Charlotte, Syrén, Per‐Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725671/
https://www.ncbi.nlm.nih.gov/pubmed/28980755
http://dx.doi.org/10.1002/cbic.201700443