Mutual independence of alkaline‐ and calcium‐mediated signalling in Aspergillus fumigatus refutes the existence of a conserved druggable signalling nexus

Functional coupling of calcium‐ and alkaline responsive signalling occurs in multiple fungi to afford efficient cation homeostasis. Host microenvironments exert alkaline stress and potentially toxic concentrations of Ca(2+), such that highly conserved regulators of both calcium‐ (Crz) and pH‐ (PacC/...

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Detalles Bibliográficos
Autores principales: Loss, Omar, Bertuzzi, Margherita, Yan, Yu, Fedorova, Natalie, McCann, Bethany L., Armstrong‐James, Darius, Espeso, Eduardo A., Read, Nick D., Nierman, William C., Bignell, Elaine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725717/
https://www.ncbi.nlm.nih.gov/pubmed/28922497
http://dx.doi.org/10.1111/mmi.13840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725717/
https://www.ncbi.nlm.nih.gov/pubmed/28922497
http://dx.doi.org/10.1111/mmi.13840

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